Transcriptomic responses to vaccination

Format

Data frame with one row per gene containing log fold changes and FDR (q values) for the Fluad vaccine as compared to placebo on day 0, day 1, day 2 and day 3 after the vaccination.

Details

The data shows the time course of transcriptomic responses to influenza vaccination in healthy volunteers. The source of the data is GEO project PRJNA515032, associated with the following paper:

Weiner, January, et al. "Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium." Scientific reports 9.1 (2019): 1-14.

For the data set, 3000 genes with top variance were chosen.